Between 1920 and 1928, Lo Medico studied at the Beaux Arts Institute of Design in New York. He was a specialist in the carving of reliefs and in the designing of medals. Among his public sculptures are a series of panels for the Wilmington, North Carolina, Courthouse (1936); Family Group for the Metropolitan Life Insurance Company (1942); World War II Aviator, executed for the Artists for Victory Exhibition; six figures of early Christian saints for the National Shrine of the Immaculate Conception, Washington, D. C.; and a number of reliefs for public schools in Queens and Staten Island, New York. Among the medals designed by Lo Medico are the Herbert Adams Memorial Award and The Seventy Fifth Anniversary Medal, both for the National Sculpture Society; The Madame Curie Medal for the Société Commemorative de Femmes Celebres; and The Patrick Henry Medal for the New York University Hall of Fame of Great Americans.
Lo Medico was a member of the National Sculpture Society, the American Numismatic Society, the Architectural League of New York, and the Allied Artists of America.
