Rose graduated from Cooper Union School of Art in 1945, attended the Art Students League in 1946, and the Hans Hofmann School in 1947. In 1974 she was awarded a grant from the New York State Council for the Arts and, that same year, was won the Altman Prize for Figure Drawing from the National Academy. She received a grant from the National Endowment for the Arts in 1977 and, in 1980 and 1988, was awarded grants from the Esther and Adolph Gottlieb Foundation.
She has had more than ten solo exhibitions in New York City and Long Island. The earliest of these was at Hansa Gallery, New York, in 1954; that was followed by an exhibition at Zabriskie Gallery in 1965. She exhibited several times at Tibor de Nagy Gallery, New York, during the 1970s and 1980s, and at Cyrus Gallery, New York in 1989. Her paintings can be found in the permanent collections of the Metropolitan Museum of Art, Syracuse University, Ciba Geigy, and Guild Hall Museum, East Hampton, New York.
She joined the faculty of the Art Students League in 1962 and has taught at Columbia University (1974) and Brooklyn College (1974). She resides in New York City.